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Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes

Autophagy defines the lifespan of eukaryotic organisms by ensuring cellular survival through regulated bulk clearance of proteins, organelles and membranes. Pathophysiological consequences of improper autophagy give rise to a variety of age-related human diseases such as cancer and neurodegeneration...

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Détails bibliographiques
Auteurs principaux: Proikas-Cezanne, Tassula, Robenek, Horst
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918056/
https://ncbi.nlm.nih.gov/pubmed/21564513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01339.x
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