BCL2 suppresses PARP1 function and non-apoptotic cell death

BCL2 suppresses apoptosis by binding the BH3 domain of pro-apoptotic factors and thereby regulating outer mitochondrial membrane permeabilization. Many tumor types, including B-cell lymphomas and chronic lymphocytic leukemia, are dependent on BCL2 for survival, but become resistant to apoptosis afte...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dutta, Chaitali, Day, Tovah, Kopp, Nadja, van Bodegom, Diederik, Davids, Matthew S., Ryan, Jeremy, Bird, Liat, Kommajosyula, Naveen, Weigert, Oliver, Yoda, Akinori, Fung, Hua, Brown, Jennifer R., Shapiro, Geoffrey I., Letai, Anthony, Weinstock, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075432/
https://ncbi.nlm.nih.gov/pubmed/22689920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-4204
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados