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Twist1- and Twist2-Haploinsufficiency Results in Reduced Bone Formation

BACKGROUND: Twist1 and Twist2 are highly homologous bHLH transcription factors that exhibit extensive highly overlapping expression profiles during development. While both proteins have been shown to inhibit osteogenesis, only Twist1 haploinsufficiency is associated with the premature synostosis of...

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Autori principali: Huang, Yanyu, Meng, Tian, Wang, Suzhen, Zhang, Hua, Mues, Gabriele, Qin, Chunlin, Feng, Jian Q., D'Souza, Rena N., Lu, Yongbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074031/
https://ncbi.nlm.nih.gov/pubmed/24971743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099331
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