Twist1- and Twist2-Haploinsufficiency Results in Reduced Bone Formation

BACKGROUND: Twist1 and Twist2 are highly homologous bHLH transcription factors that exhibit extensive highly overlapping expression profiles during development. While both proteins have been shown to inhibit osteogenesis, only Twist1 haploinsufficiency is associated with the premature synostosis of...

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Detalhes bibliográficos
Main Authors: Huang, Yanyu, Meng, Tian, Wang, Suzhen, Zhang, Hua, Mues, Gabriele, Qin, Chunlin, Feng, Jian Q., D'Souza, Rena N., Lu, Yongbo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074031/
https://ncbi.nlm.nih.gov/pubmed/24971743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099331
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