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Molecular Studies on the Roles of Runx2 and Twist1 in Regulating FGF signaling

BACKGROUND: Supernumerary teeth are often observed in patients suffering from cleidocranial dysplasia due to a mutation in Runx2 that results in haploinsufficiencty. However, the underlying molecular mechanisms are poorly defined. In this study, we assessed the roles of Runx2 and its functional anta...

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Autori principali: Lu, Yongbo, Li, Yucheng, Cavender, Adriana C., Wang, Suzhen, Mansukhani, Alka, D’Souza, Rena N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153435/
https://ncbi.nlm.nih.gov/pubmed/22972545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23858
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