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Functional evaluation of a novel tooth agenesis associated BMP4 prodomain mutation

The detection of gene mutations in patients with congenitally missing teeth is not very complicated however proving causality is often quite difficult. Here we report the detection of a substitution mutation, A42P, within the prodomain of bone morphogenetic protein-4 (BMP4) in a small family with to...

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Main Authors: Huang, Yanyu, Lu, Yongbo, Mues, Gabriele, Wang, Suzhen, Bonds, John, D’Souza, Rena
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711029/
https://ncbi.nlm.nih.gov/pubmed/23841782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eos.12055
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