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Msx1 Mutations: How Do They Cause Tooth Agenesis?

Mutations in the transcription factors PAX9 and MSX1 cause selective tooth agenesis in humans. In tooth bud mesenchyme of mice, both proteins are required for the expression of Bmp4, which is the key signaling factor for progression to the next step of tooth development. We have previously shown tha...

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Detalhes bibliográficos
Main Authors: Wang, Y., Kong, H., Mues, G., D’Souza, R.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144107/
https://ncbi.nlm.nih.gov/pubmed/21297014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034510387430
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