Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

BACKGROUND: Diabetic women are five times more likely to develop congestive heart failure compared with two fold for men. The underlying mechanism for this gender difference is not known. Here we investigate the molecular mechanisms responsible for this female disadvantage and attempt safeguarding c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Moore, Andrew, Shindikar, Amol, Fomison-Nurse, Ingrid, Riu, Federica, Munasinghe, Pujika E, Parshu Ram, Thrishila, Saxena, Pankaj, Coffey, Sean, Bunton, Richard W, Galvin, Ivor F, Williams, Michael JA, Emanueli, Costanza, Madeddu, Paolo, Katare, Rajesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073808/
https://ncbi.nlm.nih.gov/pubmed/24685144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-68
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge