Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

BACKGROUND: Diabetic women are five times more likely to develop congestive heart failure compared with two fold for men. The underlying mechanism for this gender difference is not known. Here we investigate the molecular mechanisms responsible for this female disadvantage and attempt safeguarding c...

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Opis bibliograficzny
Główni autorzy: Moore, Andrew, Shindikar, Amol, Fomison-Nurse, Ingrid, Riu, Federica, Munasinghe, Pujika E, Parshu Ram, Thrishila, Saxena, Pankaj, Coffey, Sean, Bunton, Richard W, Galvin, Ivor F, Williams, Michael JA, Emanueli, Costanza, Madeddu, Paolo, Katare, Rajesh
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2014
Hasła przedmiotowe:
Original Investigation
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073808/
https://ncbi.nlm.nih.gov/pubmed/24685144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-68
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