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Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells

Increased apoptosis and premature cellular ageing of the diabetic heart underpin the development of diabetic heart disease. The molecular mechanisms underlying these pathologies are still unclear. Here we determined the role of pro-senescence microRNA (miR)-34a in accelerating the ageing of the diab...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Fomison-Nurse, Ingrid, Saw, Eugene Eng Leng, Gandhi, Sophie, Munasinghe, Pujika Emani, Van Hout, Isabelle, Williams, Michael J. A, Galvin, Ivor, Bunton, Richard, Davis, Philip, Cameron, Vicky, Katare, Rajesh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030067/
https://ncbi.nlm.nih.gov/pubmed/29302057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0047-6
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