Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells

Increased apoptosis and premature cellular ageing of the diabetic heart underpin the development of diabetic heart disease. The molecular mechanisms underlying these pathologies are still unclear. Here we determined the role of pro-senescence microRNA (miR)-34a in accelerating the ageing of the diab...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Death Differ
Κύριοι συγγραφείς: Fomison-Nurse, Ingrid, Saw, Eugene Eng Leng, Gandhi, Sophie, Munasinghe, Pujika Emani, Van Hout, Isabelle, Williams, Michael J. A, Galvin, Ivor, Bunton, Richard, Davis, Philip, Cameron, Vicky, Katare, Rajesh
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2018
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030067/
https://ncbi.nlm.nih.gov/pubmed/29302057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0047-6
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