Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

BACKGROUND: Diabetic women are five times more likely to develop congestive heart failure compared with two fold for men. The underlying mechanism for this gender difference is not known. Here we investigate the molecular mechanisms responsible for this female disadvantage and attempt safeguarding c...

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Библиографические подробности
Главные авторы: Moore, Andrew, Shindikar, Amol, Fomison-Nurse, Ingrid, Riu, Federica, Munasinghe, Pujika E, Parshu Ram, Thrishila, Saxena, Pankaj, Coffey, Sean, Bunton, Richard W, Galvin, Ivor F, Williams, Michael JA, Emanueli, Costanza, Madeddu, Paolo, Katare, Rajesh
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073808/
https://ncbi.nlm.nih.gov/pubmed/24685144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-68
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