The Central Role of EED in the Orchestration of Polycomb Group Complexes

Polycomb Repressive Complexes 1 and 2 (PRC1 and 2) play a critical role in the epigenetic regulation of transcription during cellular differentiation, stem cell pluripotency, and neoplastic progression. Here we show that the Polycomb Group protein EED, a core component of PRC2, physically interacts...

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Détails bibliographiques
Auteurs principaux: Cao, Qi, Wang, Xiaoju, Zhao, Meng, Yang, Rendong, Malik, Rohit, Qiao, Yuanyuan, Poliakov, Anton, Yocum, Anastasia K., Li, Yong, Chen, Wei, Cao, Xuhong, Jiang, Xia, Dahiya, Arun, Harris, Clair, Feng, Felix Y., Kalantry, Sundeep, Qin, Zhaohui S., Dhanasekaran, Saravana M., Chinnaiyan, Arul M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073494/
https://ncbi.nlm.nih.gov/pubmed/24457600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4127
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