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The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation

The Polycomb group (PcG) encodes an evolutionarily conserved set of chromatin-modifying proteins that are thought to maintain cellular transcriptional memory by stably silencing gene expression1. In mouse embryos mutated for the PcG protein Eed, X-chromosome inactivation (XCI) is not stably maintain...

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Bibliographic Details
Main Authors: Kalantry, Sundeep, Mills, Kyle C., Yee, Della, Otte, Arie P., Panning, Barbara, Magnuson, Terry
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400591/
https://ncbi.nlm.nih.gov/pubmed/16415857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1351
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