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Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome
Polycomb group (PcG) proteins belonging to the polycomb (Pc) repressive complexes 1 and 2 (PRC1 and PRC2) maintain homeotic gene silencing. In Drosophila, PRC2 methylates histone H3 on lysine 27, and this epigenetic mark facilitates recruitment of PRC1. Mouse PRC2 (mPRC2) has been implicated in X in...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172612/ https://ncbi.nlm.nih.gov/pubmed/15596546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200409026 |
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