Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles

Background. Clade B DNA and recombinant modified vaccinia Ankara (MVA) vaccines producing virus-like particles displaying trimeric membrane-bound envelope glycoprotein (Env) were tested in a phase 2a trial in human immunodeficiency virus (HIV)–uninfected adults for safety, immunogenicity, and 6-mont...

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Main Authors: Goepfert, Paul A., Elizaga, Marnie L., Seaton, Kelly, Tomaras, Georgia D., Montefiori, David C., Sato, Alicia, Hural, John, DeRosa, Stephen C., Kalams, Spyros A., McElrath, M. Juliana, Keefer, Michael C., Baden, Lindsey R., Lama, Javier R., Sanchez, Jorge, Mulligan, Mark J., Buchbinder, Susan P., Hammer, Scott M., Koblin, Beryl A., Pensiero, Michael, Butler, Chris, Moss, Bernard, Robinson, Harriet L., Donastorg, Yeycy, Qin, Li, Lawrence, Dale, Cardinali, Massimo, Bae, Jin, Holt, Renée, Redinger, Huguette, Johannessen, Jan, Broder, Gail, Moody-White, Jerri, McKay, Butch, Calazans, Gabriela, Bentley, Carter, Kakinami, Lisa, Skibinski, Katie, Estep, Scharla, Tseng, Jenny, Swenson, Molly, Madenwald, Tamra, Overton, Edgar Turner, Edupuganti, Srilatha, Rouphael, Nadine, Whitaker, Jennifer, Hay, C Mhorag, Bunce, Catherine A, Gonzales, Pedro, Hurtado, Juan Carlos, Dolin, Raphael, Mayer, Ken, Walsh, Steven, Johnson, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072895/
https://ncbi.nlm.nih.gov/pubmed/24403557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu003
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