Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles

Background. Clade B DNA and recombinant modified vaccinia Ankara (MVA) vaccines producing virus-like particles displaying trimeric membrane-bound envelope glycoprotein (Env) were tested in a phase 2a trial in human immunodeficiency virus (HIV)–uninfected adults for safety, immunogenicity, and 6-mont...

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Autori principali: Goepfert, Paul A., Elizaga, Marnie L., Seaton, Kelly, Tomaras, Georgia D., Montefiori, David C., Sato, Alicia, Hural, John, DeRosa, Stephen C., Kalams, Spyros A., McElrath, M. Juliana, Keefer, Michael C., Baden, Lindsey R., Lama, Javier R., Sanchez, Jorge, Mulligan, Mark J., Buchbinder, Susan P., Hammer, Scott M., Koblin, Beryl A., Pensiero, Michael, Butler, Chris, Moss, Bernard, Robinson, Harriet L., Donastorg, Yeycy, Qin, Li, Lawrence, Dale, Cardinali, Massimo, Bae, Jin, Holt, Renée, Redinger, Huguette, Johannessen, Jan, Broder, Gail, Moody-White, Jerri, McKay, Butch, Calazans, Gabriela, Bentley, Carter, Kakinami, Lisa, Skibinski, Katie, Estep, Scharla, Tseng, Jenny, Swenson, Molly, Madenwald, Tamra, Overton, Edgar Turner, Edupuganti, Srilatha, Rouphael, Nadine, Whitaker, Jennifer, Hay, C Mhorag, Bunce, Catherine A, Gonzales, Pedro, Hurtado, Juan Carlos, Dolin, Raphael, Mayer, Ken, Walsh, Steven, Johnson, Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072895/
https://ncbi.nlm.nih.gov/pubmed/24403557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu003
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