Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles

Background. Clade B DNA and recombinant modified vaccinia Ankara (MVA) vaccines producing virus-like particles displaying trimeric membrane-bound envelope glycoprotein (Env) were tested in a phase 2a trial in human immunodeficiency virus (HIV)–uninfected adults for safety, immunogenicity, and 6-mont...

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Autors principals: Goepfert, Paul A., Elizaga, Marnie L., Seaton, Kelly, Tomaras, Georgia D., Montefiori, David C., Sato, Alicia, Hural, John, DeRosa, Stephen C., Kalams, Spyros A., McElrath, M. Juliana, Keefer, Michael C., Baden, Lindsey R., Lama, Javier R., Sanchez, Jorge, Mulligan, Mark J., Buchbinder, Susan P., Hammer, Scott M., Koblin, Beryl A., Pensiero, Michael, Butler, Chris, Moss, Bernard, Robinson, Harriet L., Donastorg, Yeycy, Qin, Li, Lawrence, Dale, Cardinali, Massimo, Bae, Jin, Holt, Renée, Redinger, Huguette, Johannessen, Jan, Broder, Gail, Moody-White, Jerri, McKay, Butch, Calazans, Gabriela, Bentley, Carter, Kakinami, Lisa, Skibinski, Katie, Estep, Scharla, Tseng, Jenny, Swenson, Molly, Madenwald, Tamra, Overton, Edgar Turner, Edupuganti, Srilatha, Rouphael, Nadine, Whitaker, Jennifer, Hay, C Mhorag, Bunce, Catherine A, Gonzales, Pedro, Hurtado, Juan Carlos, Dolin, Raphael, Mayer, Ken, Walsh, Steven, Johnson, Jennifer
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072895/
https://ncbi.nlm.nih.gov/pubmed/24403557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu003
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