Human IGF1 Regulates Midgut Oxidative Stress and Epithelial Homeostasis to Balance Lifespan and Plasmodium falciparum resistance in Anopheles stephensi

Insulin and insulin-like growth factor signaling (IIS) regulates cell death, repair, autophagy, and renewal in response to stress, damage, and pathogen challenge. Therefore, IIS is fundamental to lifespan and disease resistance. Previously, we showed that insulin-like growth factor 1 (IGF1) within a...

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Detaylı Bibliyografya
Asıl Yazarlar: Drexler, Anna L., Pietri, Jose E., Pakpour, Nazzy, Hauck, Eric, Wang, Bo, Glennon, Elizabeth K. K., Georgis, Martha, Riehle, Michael A., Luckhart, Shirley
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072789/
https://ncbi.nlm.nih.gov/pubmed/24968248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004231
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