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Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging
The number of newly formed neurons declines rapidly during aging, and this decrease in neurogenesis is associated with decreased function of neural stem/progenitor cells (NPCs). Here, we determined that a WIP1-dependent pathway regulates NPC differentiation and contributes to the age-associated decl...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071391/ https://ncbi.nlm.nih.gov/pubmed/24911145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73015 |
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