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Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging
The number of newly formed neurons declines rapidly during aging, and this decrease in neurogenesis is associated with decreased function of neural stem/progenitor cells (NPCs). Here, we determined that a WIP1-dependent pathway regulates NPC differentiation and contributes to the age-associated decl...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071391/ https://ncbi.nlm.nih.gov/pubmed/24911145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73015 |
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