Wip1 phosphatase positively modulates dendritic spine morphology and memory processes through the p38MAPK signaling pathway

Dendritic spine morphology is modulated by protein kinase p38, a mitogen-activated protein (MAPK), in the hippocampus. Protein p38MAPK is a substrate of wip1, a protein phosphatase. The role of wip1 in the central nervous system (CNS) has never been explored. Here, we report a novel function of wip1...

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Main Authors: Fernandez, Francesca, Soon, Irene, Li, Zeng, Kuan, Tan Chee, Min, Deng Hong, Wong, Esther Sook-Miin, Demidov, Oleg N., Paterson, Malcolm C., Dawe, Gavin, Bulavin, Dmitry V., Xiao, Zhi-Cheng
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478255/
https://ncbi.nlm.nih.gov/pubmed/22983193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.20892
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