Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase

The ataxia telangiectasia mutated (ATM) kinase is a key tumor suppressor that regulates numerous cell cycle checkpoints as well as apoptosis. Here, we report that ATM is a critical player in the regulation of apoptosis and lymphomagenesis in the presence of c-myc. In turn, deletion of the inhibitory...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Shreeram, Sathyavageeswaran, Hee, Weng Kee, Demidov, Oleg N., Kek, Calvina, Yamaguchi, Hiroshi, Fornace, Albert J., Anderson, Carl W., Appella, Ettore, Bulavin, Dmitry V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
Soggetti:
Brief Definitive Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118180/
https://ncbi.nlm.nih.gov/pubmed/17158963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061563
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi