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Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase
The ataxia telangiectasia mutated (ATM) kinase is a key tumor suppressor that regulates numerous cell cycle checkpoints as well as apoptosis. Here, we report that ATM is a critical player in the regulation of apoptosis and lymphomagenesis in the presence of c-myc. In turn, deletion of the inhibitory...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118180/ https://ncbi.nlm.nih.gov/pubmed/17158963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061563 |
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