Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease

Abstract. Our previous findings demonstrated an increase in pulmonary mast cells (MCs) in idiopathic pulmonary arterial hypertension (IPAH). Also, literature suggests a potential role for MCs in chronic obstructive pulmonary disease (COPD). However, a comprehensive investigation of lungs from patien...

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Hauptverfasser: Kosanovic, Djuro, Dahal, Bhola Kumar, Peters, Dorothea Maren, Seimetz, Michael, Wygrecka, Malgorzata, Hoffmann, Katrin, Antel, Jochen, Reiss, Irwin, Ghofrani, Hossein Ardeschir, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Schermuly, Ralph Theo
Format: Artigo
Sprache:Inglês
Veröffentlicht: University of Chicago Press 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070756/
https://ncbi.nlm.nih.gov/pubmed/25006428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/675642
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