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Structural Basis for Protein anti-Aggregation Activity of the Trigger Factor Chaperone*
Molecular chaperones prevent aggregation and misfolding of proteins but scarcity of structural data has impeded an understanding of the recognition and anti-aggregation mechanisms. Here we report the solution structure, dynamics and energetics of three Trigger Factor (TF) chaperone molecules in comp...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070327/ https://ncbi.nlm.nih.gov/pubmed/24812405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1250494 |
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