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Structural Basis for Protein anti-Aggregation Activity of the Trigger Factor Chaperone*

Molecular chaperones prevent aggregation and misfolding of proteins but scarcity of structural data has impeded an understanding of the recognition and anti-aggregation mechanisms. Here we report the solution structure, dynamics and energetics of three Trigger Factor (TF) chaperone molecules in comp...

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Bibliografiska uppgifter
Huvudupphovsmän: Saio, Tomohide, Guan, Xiao, Rossi, Paolo, Economou, Anastassios, Kalodimos, Charalampos G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070327/
https://ncbi.nlm.nih.gov/pubmed/24812405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1250494
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