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Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells

Receptor targeting ligands for imaging and/or therapy of cancer are limited by heterogeneity of receptor expression by tumor cells, both inter-patient and intra-patient. It is often more important for imaging agents to identify local and distant spread of disease than it is to identify a specific re...

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Autors principals: Shrivastava, Ajay, Wang, Shu-Huei, Raju, Natarajan, Gierach, Izabela, Ding, Haiming, Tweedle, Michael F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070312/
https://ncbi.nlm.nih.gov/pubmed/23265893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.11.110
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