A High-Affinity Near-Infrared Fluorescent Probe to Target Bombesin Receptors

PURPOSE: This study aimed to create new optical surgical navigation NIRF probes for prostate and breast cancers. PROCEDURES: IR800-linker-QWAVGHLM-NH(2) with linker = GSG, GGG, and G-Abz4 were synthesized and characterized. IC(50) for bombesin receptors (BBN-R) in PC-3 prostate and T47D breast cance...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Shrivastava, Ajay, Ding, Haiming, Kothandaraman, Shankaran, Wang, Shu-Huei, Gong, Li, Williams, Michelle, Milum, Keisha, Zhang, Song, Tweedle, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885141/
https://ncbi.nlm.nih.gov/pubmed/24604209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0727-2
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