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Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics

Drug transporter expression in tissues (in vivo) usually differs from that in cell lines used to measure transporter activity (in vitro). Therefore, quantification of transporter expression in tissues and cell lines is important to develop scaling factor for in vitro to in vivo extrapolation (IVIVE)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Prasad, Bhagwat, Unadkat, Jashvant D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer US 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070263/
https://ncbi.nlm.nih.gov/pubmed/24752720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9602-y
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