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Structure-based Programming of Lymph Node Targeting in Molecular Vaccines

In cancer patients, visual identification of sentinel lymph nodes (LNs) is achieved by the injection of dyes that bind avidly to endogenous albumin, targeting these compounds to LNs where they are efficiently filtered by resident phagocytes(1,2). Here we translate this “albumin hitchhiking” approach...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Haipeng, Moynihan, Kelly D., Zheng, Yiran, Szeto, Gregory L., Li, Adrienne V., Huang, Bonnie, Van Egeren, Debra S., Park, Clara, Irvine, Darrell J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069155/
https://ncbi.nlm.nih.gov/pubmed/24531764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12978
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