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Structure-based Programming of Lymph Node Targeting in Molecular Vaccines

In cancer patients, visual identification of sentinel lymph nodes (LNs) is achieved by the injection of dyes that bind avidly to endogenous albumin, targeting these compounds to LNs where they are efficiently filtered by resident phagocytes(1,2). Here we translate this “albumin hitchhiking” approach...

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Detalhes bibliográficos
Main Authors: Liu, Haipeng, Moynihan, Kelly D., Zheng, Yiran, Szeto, Gregory L., Li, Adrienne V., Huang, Bonnie, Van Egeren, Debra S., Park, Clara, Irvine, Darrell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069155/
https://ncbi.nlm.nih.gov/pubmed/24531764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12978
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