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Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines
B-cells are promising candidate autologous antigen-presenting cells (APCs) to prime antigen-specific T-cells both in vitro and in vivo. However to date, a significant barrier to utilizing B-cells as APCs is their low capacity for non-specific antigen uptake compared to “professional” APCs such as de...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441198/ https://ncbi.nlm.nih.gov/pubmed/25999171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10276 |
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