Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex Virus 1 Infection Model

Herpes simplex virus (HSV) infections can cause considerable morbidity. Transmission of HSV-2 has become a major health concern, since it has been shown to promote transmission of other sexually transmitted diseases. Pritelivir (AIC316, BAY 57-1293) belongs to a new class of HSV antiviral compounds,...

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Bibliografiske detaljer
Main Authors: Biswas, Subhajit, Sukla, Soumi, Goldner, Thomas, Field, Hugh J., Kropeit, Dirk, Paulsen, Daniela, Welbers, André, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Birkmann, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068558/
https://ncbi.nlm.nih.gov/pubmed/24752278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02641-14
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