Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells

Endothelial cell (ECs) lining blood vessels express many mechanosensors, including platelet endothelial cell adhesion molecule-1 (PECAM-1), that convert mechanical force to biochemical signals. While it is accepted that mechanical stresses and the mechanical properties of ECs regulate vessel health,...

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Main Authors: Collins, Caitlin, Osborne, Lukas D., Guilluy, Christophe, Chen, Zhongming, O’Brien, E Tim, Reader, John S., Burridge, Keith, Superfine, Richard, Tzima, Ellie
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068264/
https://ncbi.nlm.nih.gov/pubmed/24917553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4984
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