Use of a specific antidote to dabigatran (idarucizumab) reduces blood loss and mortality in dabigatran-induced and trauma-induced bleeding in pigs

Benzer Materyaller

• In a trauma experimental pig model prothrombin complex concentrates and a specific antidote (idarucizumab) are effective to reverse the anticoagulant effects of dabigatran
  Yazar:: Grottke, O, ve diğerleri
  Baskı/Yayın Bilgisi: (2014)
• Prothrombin complex concentrate restores haemostasis in a dabigatran anticoagulated polytrauma pig model
  Yazar:: Honickel, M, ve diğerleri
  Baskı/Yayın Bilgisi: (2014)
• Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution
  Yazar:: Grottke, Oliver, ve diğerleri
  Baskı/Yayın Bilgisi: (2019)
• Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model
  Yazar:: Grottke, Oliver, ve diğerleri
  Baskı/Yayın Bilgisi: (2014)
• Efficacy of idarucizumab, prothrombin complex concentrate (PCC) and activated PCC to reverse the anticoagulatory potential of dabigatran in a porcine polytrauma model
  Yazar:: Honickel, M, ve diğerleri
  Baskı/Yayın Bilgisi: (2015)