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SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination

Translesion DNA synthesis (TLS) is a universal DNA damage tolerance mechanism conserved from yeast to mammals. A key event in the regulation of TLS is the monoubiquitination of proliferating cell nuclear antigen (PCNA). Extensive evidence indicates that the RAD6–RAD18 ubiquitin-conjugating/ligase co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Han, Jinhua, Liu, Ting, Huen, Michael S.Y., Hu, Lin, Chen, Zhiqiu, Huang, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068132/
https://ncbi.nlm.nih.gov/pubmed/24958773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311007
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