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A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA

SUMO-targeted ubiquitin ligases (STUbLs) recognize sumoylated proteins as substrates for ubiquitylation and have been implicated in several aspects of DNA repair and the damage response. However, few physiological STUbL substrates have been identified, and the relative importance of SUMO binding ver...

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Autors principals: Parker, Joanne L., Ulrich, Helle D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526273/
https://ncbi.nlm.nih.gov/pubmed/23034805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks892
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