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SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination
Translesion DNA synthesis (TLS) is a universal DNA damage tolerance mechanism conserved from yeast to mammals. A key event in the regulation of TLS is the monoubiquitination of proliferating cell nuclear antigen (PCNA). Extensive evidence indicates that the RAD6–RAD18 ubiquitin-conjugating/ligase co...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068132/ https://ncbi.nlm.nih.gov/pubmed/24958773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311007 |
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