Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT associated proteins

The G-rich single stranded DNA at the 3′ end of human telomeres can self-fold into G-quaduplex (GQ). However, telomere lengthening by telomerase or the recombination-based alternative lengthening of telomere (ALT) mechanism requires protein loading on the overhang. Using single molecule fluorescence...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hwang, Helen, Kreig, Alex, Calvert, Jacob, Lormand, Justin, Kwon, Yongho, Daley, James M., Sung, Patrick, Opresko, Patricia L., Myong, Sua
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067947/
https://ncbi.nlm.nih.gov/pubmed/24836024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.03.013
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы