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Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca(2+)/H(+) Antiporter
Mitochondria are integral components of cellular calcium (Ca(2+)) signaling. Calcium stimulates mitochondrial adenosine 5′-triphosphate production, but can also initiate apoptosis. In turn, cytoplasmic Ca(2+) concentrations are regulated by mitochondria. Although several transporter and ion-channel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067766/ https://ncbi.nlm.nih.gov/pubmed/19797662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175145 |
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