Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

Recent studies by our group and others demonstrated a required and conserved role of Stim in store-operated Ca(2+) influx and Ca(2+) release-activated Ca(2+) (CRAC) channel activity. By using an unbiased genome-wide RNA interference screen in Drosophila S2 cells, we now identify 75 hits that strongl...

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Detalhes bibliográficos
Main Authors: Zhang, Shenyuan L., Yeromin, Andriy V., Zhang, Xiang H.-F., Yu, Ying, Safrina, Olga, Penna, Aubin, Roos, Jack, Stauderman, Kenneth A., Cahalan, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482614/
https://ncbi.nlm.nih.gov/pubmed/16751269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603161103
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