Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

For efficient development of an immune response, T lymphocytes require long-lasting calcium influx through calcium release-activated calcium (CRAC) channels and the formation of a stable immunological synapse (IS) with the antigen-presenting cell (APC). Recent RNAi screens have identified Stim and O...

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Bibliographische Detailangaben
Hauptverfasser: Lioudyno, Maria I., Kozak, J. Ashot, Penna, Aubin, Safrina, Olga, Zhang, Shenyuan L., Sen, Debasish, Roos, Jack, Stauderman, Kenneth A., Cahalan, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538873/
https://ncbi.nlm.nih.gov/pubmed/18250319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706122105
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