From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects

The superordinate principles governing the transcriptome response of differentiating cells exposed to drugs are still unclear. Often, it is assumed that toxicogenomics data reflect the immediate mode of action (MoA) of drugs. Alternatively, transcriptome changes could describe altered differentiatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Balmer, Nina V., Klima, Stefanie, Rempel, Eugen, Ivanova, Violeta N., Kolde, Raivo, Weng, Matthias K., Meganathan, Kesavan, Henry, Margit, Sachinidis, Agapios, Berthold, Michael R., Hengstler, Jan G., Rahnenführer, Jörg, Waldmann, Tanja, Leist, Marcel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2014
Gaiak:
Reproductive Toxicology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067541/
https://ncbi.nlm.nih.gov/pubmed/24935251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1279-6
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