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Building a fission machine – structural insights into dynamin assembly and activation

Dynamin is a large multidomain GTPase that assembles into helical arrays around the necks of deeply invaginated clathrin-coated pits and catalyzes membrane fission during the final stages of endocytosis. Although it is well established that the function of dynamin in vivo depends on its oligomerizat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chappie, Joshua S., Dyda, Fred
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067269/
https://ncbi.nlm.nih.gov/pubmed/23781021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.108845
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