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Structure of a mitochondrial fission dynamin in the closed conformation

Dynamin 1-like proteins (DNM1-L) are mechanochemical GTPases that induce membrane fission in mitochondria and peroxisomes. Their mechanism depends on conformational changes driven by nucleotide and lipid cycling. Here we show the crystal structure of a mitochondrial fission dynamin (CmDnm1) from the...

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Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Bohuszewicz, Olga, Low, Harry H.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104806/
https://ncbi.nlm.nih.gov/pubmed/30061604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0097-6
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