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A dynamin mutant defines a super-constricted pre-fission state
Dynamin is a 100 kDa GTPase that organizes into helical assemblies at the base of nascent clathrin-coated vesicles. Formation of these oligomers stimulates the intrinsic GTPase activity of dynamin, which is necessary for efficient membrane fission during endocytosis. Recent evidence suggests that th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142656/ https://ncbi.nlm.nih.gov/pubmed/25088425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.054 |
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