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A pseudo-atomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke
The GTPase dynamin catalyzes membrane fission. Though this process requires dynamin assembly, G domain dimerization and stimulated GTP hydrolysis, the underlying structural interactions and conformational changes remain a mystery. Here we present the GMPPCP-bound structures of the truncated human dy...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185303/ https://ncbi.nlm.nih.gov/pubmed/21962517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.003 |
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