A pseudo-atomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke

The GTPase dynamin catalyzes membrane fission. Though this process requires dynamin assembly, G domain dimerization and stimulated GTP hydrolysis, the underlying structural interactions and conformational changes remain a mystery. Here we present the GMPPCP-bound structures of the truncated human dy...

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Bibliographic Details
Main Authors: Chappie, Joshua S., Mears, Jason A., Fang, Shunming, Leonard, Marilyn, Schmid, Sandra L., Milligan, Ronald A., Hinshaw, Jenny E., Dyda, Fred
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185303/
https://ncbi.nlm.nih.gov/pubmed/21962517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.003
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