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Glucocorticoid Receptor β Stimulates Akt1 Growth Pathway by Attenuation of PTEN

Glucocorticoids (GCs) are known inhibitors of proliferation and are commonly prescribed to cancer patients to inhibit tumor growth and induce apoptosis via the glucocorticoid receptor (GR). Because of alternative splicing, the GR exists as two isoforms, GRα and GRβ. The growth inhibitory actions of...

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書誌詳細
主要な著者: Stechschulte, Lance A., Wuescher, Leah, Marino, Joseph S., Hill, Jennifer W., Eng, Charis, Hinds, Terry D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067219/
https://ncbi.nlm.nih.gov/pubmed/24817119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544072
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