Discovery of Glucocorticoid Receptor-β in Mice with a Role in Metabolism

Glucocorticoid hormones control diverse physiological processes, including metabolism and immunity, by activating the major glucocorticoid receptor (GR) isoform, GRα. However, humans express an alternative isoform, human (h)GRβ, that acts as an inhibitor of hGRα to produce a state of glucocorticoid...

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Hlavní autoři: Hinds, Terry D., Ramakrishnan, Sadeesh, Cash, Harrison A., Stechschulte, Lance A., Heinrich, Garrett, Najjar, Sonia M., Sanchez, Edwin R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940475/
https://ncbi.nlm.nih.gov/pubmed/20660300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0411
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