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Glucocorticoid Receptor β Stimulates Akt1 Growth Pathway by Attenuation of PTEN
Glucocorticoids (GCs) are known inhibitors of proliferation and are commonly prescribed to cancer patients to inhibit tumor growth and induce apoptosis via the glucocorticoid receptor (GR). Because of alternative splicing, the GR exists as two isoforms, GRα and GRβ. The growth inhibitory actions of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067219/ https://ncbi.nlm.nih.gov/pubmed/24817119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544072 |
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