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Cancer-relevant Splicing Factor CAPERα Engages the Essential Splicing Factor SF3b155 in a Specific Ternary Complex

U2AF homology motifs (UHMs) mediate protein-protein interactions with U2AF ligand motifs (ULMs) of pre-mRNA splicing factors. The UHM-containing alternative splicing factor CAPERα regulates splicing of tumor-promoting VEGF isoforms, yet the molecular target of the CAPERα UHM is unknown. Here we pres...

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Detalles Bibliográficos
Main Authors: Loerch, Sarah, Maucuer, Alexandre, Manceau, Valérie, Green, Michael R., Kielkopf, Clara L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067167/
https://ncbi.nlm.nih.gov/pubmed/24795046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558825
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