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DIFFERENT REQUIREMENTS OF THE KINASE AND UHM DOMAINS OF KIS FOR ITS NUCLEAR LOCALIZATION AND BINDING TO SPLICING FACTORS

The protein kinase KIS is made by the juxtaposition of a unique kinase domain and a C-terminal domain with a U2AF Homology Motif (UHM), a sequence motif for protein interaction initially identified in the heterodimeric pre-mRNA splicing factor U2AF. This domain of KIS is closely related to the C-ter...

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Detalhes bibliográficos
Main Authors: Manceau, Valérie, Kielkopf, Clara L., Sobel, André, Maucuer, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632974/
https://ncbi.nlm.nih.gov/pubmed/18588901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.026
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